One of the most pressing issues in human and ecological health is the abundance of poly and perfluoroalkyl substances (PFAS) and phthalate esters (PAEs) in our ecosystem — two classes of synthetic chemicals known as ‘forever chemicals.’ In addition to their destructive nature affecting wildlife, soil, and agriculture, they are also responsible for causing human health problems such as liver damage, thyroid disease, obesity, fertility issues, and cancer.

While scientists worldwide are racing to learn more about how to combat PFAS and PAEs in a variety of settings, Kirin Emlet Furst*, who was previously an Assistant Professor in George Mason’s Civil, Environmental and Infrastructure Engineering Department, was focused on PFAS AND PAEs in water treatment and wastewater reuse. (Furst has since moved on to join the faculty at 4-VA partner school Virginia Tech.)
Furst reasoned that wastewater treatment facilities are a major avenue through which PFAS and PAEs can contaminate drinking water and air, as many of these compounds are insufficiently removed by common treatment processes. Furst specifically wanted to explore the air-water interface. PFAS have a high surface activity which results in their attraction to the air-water interface. And while PAEs have a lower surface activity, they might be attracted to other materials that accumulate at the air-water interface. Research in full-scale treatment systems was needed to understand these interactions.
The 4-VA@George Mason Advisory Board recognized the importance of this research and awarded Furst’s 4-VA proposal, “The role of the air-water interface in breakthrough of PFAS and phthalate esters during wastewater treatment.”
Joining Furst in the research was 4-VA partner Zhiwu (Drew) Wang, a specialist in wastewater treatment and biological processes at Virginia Tech. Furst also tapped Mason graduate student Meghana Kuppa who was already developing analytical methods to measure PFAS and PAEs. Ethan Gasper, an undergraduate in the Department of Chemistry and Biochemistry, assisted Kuppa with much of the bench work on the project.
Kuppa collected water samples and scum, which is the material that accumulates at the air-water interface, from process unit tanks at a wastewater treatment plant to measure the target contaminants and water quality parameters known to impact partitioning behavior. Their goal? Quantify the role of the air-water interface in enabling breakthrough of PFAS and PAEs in wastewater treatment facilities and identify potential engineering solutions.


Although developing the complex methodologies for the project was a challenge, several important outcomes were realized. First, high levels of multiple PFAS were found in the scum from both the primary and secondary treatment processes. The team concluded that the PFAS levels in the primary scum samples, especially, were much higher than they could accurately measure due to interference from particulates and oily substances in the method. However, analysis of the secondary determined any PFAS present during secondary treatment is more likely to be found in the treated water and may also contaminate the facility air due to aeration in these tanks.
While fewer PAEs were found in the scum samples, Kuppa’s experiments show that phthalates can sorb to organic material in the scum. This sorption may contribute to the difficulty in removing phthalates during wastewater treatment.
Furst reflects on the research and the 4-VA funding noting, “The 4-VA award empowered my group to pursue this new line of research and helped to support Kuppa’s innovative thesis projects. Plus, now we have preliminary data to pursue NSF and other high-impact external funding.”


















Today, to Luther’s great delight, the results have proved far more successful than he could have ever anticipated. Tens of thousands of animal images from camera traps and audio recordings have already been collected.
Hassan, Jordan Seidmeyer, Katie Russell, Carolian Sanabria, Adrian Em, Alix Upchurch, Piper Robinson, Tristan Silva-Montoya, and Estefany Umana spent hours creating this treasure trove of records. Emilia Roberts, a MS student in ESP, managed these undergraduate researchers.
The project continues to gain traction. The team has created a website featuring the results of the acoustic portion of the research,
This was achieved following 4-VA’s approval of a proposal by George Mason’s Yun Yu, an Assistant Professor in Chemistry and Biochemistry Department, for a grant entitled

Angeline Lillard, a widely respected developmental psychologist and researcher in the Department of Psychology at UVA. Explains Doebel, “Our collaboration would not have taken off the way it did if it hadn’t been for Angeline, because she was the one who sent me an email about 4-VA. She said, ‘Have you heard of 4-VA? We should consider this option.’”


Led by Myeong Lee, Mason’s Assistant Professor of Information Science and the Director of the Community Informatics Lab, the researchers also included former College of Science faculty members Olga Gkountouna, who assisted with machine learning model development, and Ron Mahabir who provided insight on geographical data analysis. Amr Hilal of Virginia Tech helped with data analytics from a machine learning perspective.
in their geographical area, it tends to attract more participants. In a second finding, the team implemented three advanced machine learning models to predict the success of local Meetup groups, finding that the performances of these prediction models vary across different categories and cities, with some outperforming the state-of-the-art models.